Treatment

Cell therapy, also known as regenerative medicine, is a relatively new branch of medicine focused on the processes of creating, engineering and regenerating human cells, tissues and organs in order to restore or achieve their normal functions. This field promises that damaged tissues and organs can be “repaired” by stimulating the body’s repair mechanisms to functionally heal previously damaged or dysfunctional tissues or organs.  As early as 700 B.C., the ancient Greeks believed that it was possible to regenerate various parts of the body. Invented in the late 19th century, skin-grafting can be considered the earliest major attempt to recreate body tissue to restore its structure and function. Advances in body part transplantation in the 20th century further encouraged the theory that body parts can regenerate and grow new healthy cells.

The original definition of regenerative medicine, designed for broad application, includes cell and stem cell therapies, gene therapy, tissue engineering, genomic medicine, personalized medicine, biomechanical prosthetics, recombinant proteins and antibody therapies. It also includes the more familiar chemical pharmacopoeia – in short, any intervention that restores a person’s health.

Why is there such interest in stem cells?

Recently, stem cell therapy has been seen as the most viable option for a wide range of disorders where conventional therapies have not been entirely successful. Various clinical studies have confirmed significant improvement in health problems after the application of stem cell therapy. Stem cells have the power to repair damaged tissues in our body besides eliminating symptoms and play also a key role in rejuvenation.

Stem cell therapy procedures work by releasing anti-inflammatory, anti-apoptotic and anti-fibrotic signals which subsequently create an environment conducive to wound healing and tissue regeneration. As wounds heal, normal function is restored and pain becomes reduced.

Stem cells mediate repair through five primary mechanisms:

  1. provide an anti-inflammatory effect,
  2. guidance of damaged tissues and recruitment of other cells such as endothelial progenitor cells that are necessary for tissue growth,
  3. supporting the tissue remodelling over scar formation,
  4. inhibition of apoptosis
  5. differentiation into bone, cartilage, tendon and connective tissue

Stem cell treatment possibilities

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Neurological disorders

Autism

Improvements expected after cell application:

  • Improvement in cognitive functions
  • Improved memory, eye contact, learning and verbal abilities
  • Improved behaviour, stamina and patience
  • Improved psychological confidence and social adjustment (to make sure the world around your child does not cause him/her negative emotions).
  • Improved self-care
  • Improved gastrointestinal function (better digestion)
  • Strengthening of the immune system

Alzheimer's disease

Improvements expected after cell application:

  • Improvement in patient’s general condition; sleep and appetite; normalization of weight
  • improvement in perception of the environment
  • improvement of memory
  • reduction of physical and neurological symptoms of the disease
  • overall improvement in quality of life

Parkinson's disease

Improvements expected after cell application:

  • Reduction in akinesia, rigidity and tremor amplitude
  • Psycho-emotional and cognitive improvements
  • Reduction of vegetative abnormalities
  • Improvement in gait and speech
  • Post-traumatic CNS damage
  • Chronic fatigue syndrome
  • Amyotrophic lateral sclerosis
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Musculoskeletal problems

Arthritis

Improvements expected after cell application:

  • Inhibition of disease progression and milder disease development
  • reduction of joint inflammation (reduction of pain, oedema, palpitations)
  • reduced weakness and morning stiffness
  • improved functional capacity and daily life activity
  • overall improvement in quality of life

Osteoarthritis

Improvements expected after cell application:

  • Restoration of joint structures
  • slowing down of degenerative changes
  • reduced pain syndrome
  • improvement of joint mobility
  • postponement of surgical treatment
  • reduction of movement micro-injuries caused by regular exertion
  • improvement in the quality of joint and connective tissue
  • bigger muscle strength
  • Complication of sports injuries
  • Improvement in sports performance
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Endocrine disorders

Diabetes

In combination with traditional treatments for type 1 diabetes, stem cells can help:

  • reduce auto aggression of immune cells against β-cells
  • prevent the destruction of functional pancreatic β-cells
  • restore the patient’s own pancreatic β-cells and improve their functional capacity
  • prevent diabetes-related complications, which mainly affect the eyes, kidneys, peripheral nerves, etc.
  • improve the condition of insulin-dependent tissues

In type 2 diabetes, stem cells can help to:

  • restore the sensitivity of peripheral tissues to insulin
  • reduce atherogenic hyperinsulinemia
  • reduce the production of glucose and pathological lipids by liver cells
  • improve the condition of arterial walls
  • reduce the patient’s medication doses

Diabetic foot

Improvements expected after cell application:

  • reduction in the healing time of the defect / diabetic gangrene
  • reduction in the healing time of neuropathic ulcer
  • formation of a new healthy tissue and blood vessels
  • Thyroid disorders
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Cardiovascular disorders

  • Stroke
  • Cardiovascular disease

Erectile dysfunction

Improvements expected after cell application:

  • Improved potency and libido
  • Normalization of erection
  • Normalization of hormonal balance
  • Better functioning of internal organs
  • Retreat of chronic fatigue
  • Improvement of sleep and mood
  • Strengthening of the immune system
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Diseases of the digestive tract

  • Crohn’s disease
  • Cirrhosis of the liver
  • Peptic ulcers
  • Chronic pancreatitis
  • Ulcerative colitis
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Respiratory diseases

Cystic fibrosis

Improvements expected after cell application:

  • Improvement in breathing
  • Improved functional capacity and daily life activity
  • Reduction in the use of oxygen apparatus
  • Overall improvement in quality of life
  • Chronic obstructive pulmonary disease
  • Asthma
  • Chronic rhinitis
  • post-COVID therapy
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Autoimmune diseases

  • Lupus
  • Rheumatoid arthritis

Sclerosis multiplex

Improvements expected after cell application:

  • Shorter exacerbation periods and longer periods of remission
  • Less spasticity, better gait and balance
  • Better speech, emotional and cognitive improvements
  • Strengthening of the immune system
  • Improved function of the heart, kidneys, liver and intestines
  • Improved quality of life
  • Chance to return to work if patient undergoes treatment in the early stages of SM
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Other

  • Infertility
  • Sexual disorders
  • Anti-aging
  • Aesthetic applications – treatment of skin problems
  • Wilson’s disease
  • Huntington’s disease

“We take a multidisciplinary, holistic approach to each patient in a variety of ways including diet, rehabilitation, supplementation, regenerative medicine therapies, stem cell therapy and patient education.”

Which stem cells do we use during the application?

Human umbilical cord blood stem cells

Umbilical cord blood is donated voluntarily by a mother who is under the supervision of a gynaecologist and has undergone blood tests for hepatitis B, hepatitis C, HIV and syphilis with negative results at least twice during pregnancy. These cells have foetal characteristics and do not have surface antigens and therefore do not induce the graft-versus-host rejection (GvHD).

After the delivery of a healthy baby, blood is collected from umbilical cord and placenta under sterile conditions. The stem cells are then isolated in a specialized laboratory. The cells are screened for microbial contamination by doing tests required according to the law to exclude the presence of hepatitis B, hepatitis C, HIV or syphilis. Only cells that have passed all the tests may be transplanted. The cell application is carried out in different ways, individually, according to the needs and diagnosis of the patient.

Human umbilical cord mesenchymal stem cells

The umbilical cord is voluntarily donated by the mother who is screened during pregnancy, blood tests for hepatitis B, hepatitis C, HIV and syphilis are performed at least twice during pregnancy with negative results. Stem cells are isolated from Wharton’s gel – jelly from the umbilical cord. These cells have foetal characteristics and lack surface antigens and therefore do not induce the graft-versus-host rejection (GvHD).

The umbilical cord is collected after birth from a healthy foetus under sterile conditions, followed by its processing in the laboratory. Isolated cells are tested for microbial contamination, ruling out the presence of hepatitis B, hepatitis C, HIV or syphilis. Only cells that have passed all the tests can be transplanted. The stem cells are then injected in different ways according to the patient’s disease. They can be used in patients of any age and are also suitable for patients with autoimmune disorders.

Human stem cells isolated from adipose tissue

Under aseptic conditions, under local anaesthesia, approximately 100-150 ml of adipose tissue is removed from the patient’s abdominal area by liposuction and immediately sent to the laboratory for further processing. The cells are processed, isolated and injected after about 3 hours. They can be injected in patients aged 18-60 years and there is no risk of genetic disorders.